AUSCULTATION SYSTEM FOR ACQUISITION OF VASCULAR SOUNDS – TOWARDS SOUND-BASED MONITORING OF THE CAROTID ARTERY




Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trialsResearch in context

Background: This study assessed the immunogenicity of pegvaliase (recombinant Anabaena variabilis Ice Cream Scoops phenylalanine [Phe] ammonia lyase [PAL] conjugated with polyethylene glycol [PEG]) treatment in adults with phenylketonuria (PKU) and its impact on safety and efficacy.Methods: Immunogenicity was assessed during induction, upward titra

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The Landscape of Noncoding RNA in Pulmonary Hypertension

The transcriptome of pulmonary hypertension (PH) is complex and highly genetically heterogeneous, with noncoding ORIGINAL BLEND COFFEE SUBSTITUT RNA transcripts playing crucial roles.The majority of RNAs in the noncoding transcriptome are long noncoding RNAs (lncRNAs) with less circular RNAs (circRNAs), which are two characteristics gaining increas

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